Saturday, September 30, 2017
Roku (ROKU) started trading on the Nasdaq on 28 Sept 17
- After pricing its IPO Wednesday at $14 per share, Roku finished its first day of trading at $23.50, up nearly 68 percent. And by the end of Friday, Roku closed at $26.54.
- The company is now valued at about $2.6 billion.
Description
Roku, Inc. is a United States-based company engaged in creating streaming platform for delivering entertainment to the television. The Company’s products include Roku 4, Roku 3, Roku 2, Roku 1, Roku Streaming Stick and accessories, such as cables, remote controls, power adapters and headphones. Its Roku streaming players and the Roku Streaming Stick are sold through retailers in the United States, Canada, the United Kingdom, the Republic of Ireland, Mexico and France. It licenses a reference design and operating system to television manufacturers to create co-branded Roku TV models. Under the Roku Powered program, it licenses its streaming platform to pay television providers who want to use the Internet to deliver entertainment services through streaming players. It sells Roku streaming players in retail, through its licensing arrangements with television original equipment manufacturers and pay television operators.
Address
12980 Saratoga Ave Ste D
SARATOGA, CA 95070-4659
United States
SARATOGA, CA 95070-4659
United States
Website
https://www.roku.comKey stats and ratios
| Q2 (Jun '17) | 2016 | |
| Net profit margin | -15.57% | -10.73% |
| Operating margin | -13.43% | -10.88% |
| EBITD margin | - | -9.63% |
| Return on average assets | -34.84% | -24.05% |
| Return on average equity | - | - |
| Employees | 696 |
Friday, September 29, 2017
Thursday, September 28, 2017
Gold Standard Ventures (GSV) : to commence Drilling at the Lewis Project, Battle Mountain District, Nevada
Founded: 2004
goldstandardv.com
Gold Standard Ventures will commence a drill program in mid-October at its 100%-owned Lewis Project in the Battle Mountain mining district, Lander County, Nevada
Highlights
- Completing core hole BVM16C-03B which was suspended due to adverse weather conditions in January, 2017. The hole was halted in visually-encouraging alteration above the targeted permissive host formations (Antler Sequence).
- Site MGH-F will test for the down-dip extension of the Phoenix deposit which has the potential for high grade gold-silver deposits in Antler Peak Limestone similar to the adjacent Lower Fortitude deposit that produced 1.9 moz of gold and 7.5 moz of silver at an average grade of 8 g/t gold and 32 g/t silver. {See Cary, et al., 2000, Geology, skarn alteration, and Au-Cu-Ag mineralization of the Phoenix project, (Battle Mountain mining district), Lander County, Nevada, in Cluer, J.K., Price, J.G., Struhsacker, E.M., Hardyman, R.F., and Morris, C.L., eds., Geology and Ore Deposits 2000: The Great Basin and Beyond: Geological Society of Nevada, Symposium Proceedings, May 15-18, 2000, p. 1021-1045. (See Table 1)}
- One RC precollar/core tail hole is planned in the Southwest target area to offset by 300 m a 17 m skarn intercept drilled by Barrick Gold grading 5.7 g/t Au (from 776 to 793 m in FWL-30 using a 2.5 g/t cutoff). The bottom of this interval has 4.6 meters of 9 g/t Au and 21 g/t Ag. This hole will also test for Fortitude-style gold mineralization in Antler Peak Limestone.
Zynerba Pharma (ZYNE) : positive results of cannabidiol (CBD) gel in pediatric and adolescent patients with Fragile X syndrome
- Sector(s): Healthcare
- Industry: Drug Manufacturers—Specialty & Generic
- Full Time Employees: 28
- Founded in 2007
- Headquartered in Devon, Pennsylvania
- http://zynerba.com
Zynerba Pharma announces 'positive' top line results from an open label exploratory Phase 2 FAB-C clinical trial evaluating ZYN002 cannabidiol (CBD) gel in pediatric and adolescent patients with Fragile X syndrome
ZYN002 successfully met the primary endpoint and showed clinically 'meaningful improvements'
- ZYN002 also achieved clinically meaningful improvements in all measures of the Aberrant Behavior Checklist for Fragile X (ABC-FXS), which address the key symptoms of FXS including social avoidance, temper tantrums, repetitive movements, and hyperactivity.
- "The data from the FAB-C trial are very exciting and demonstrate that ZYN002 may have a profound effect on improving many of the most disabling symptoms of Fragile X, such as anxiety and difficult behaviors."
- With these data, Zynerba anticipates that it will meet with the FDA in the first half of 2018 with the goal of moving quickly into a pivotal Phase 2/3 program in pediatric and adolescent patients with FXS in 2018.
** charts before **
Friday, September 22, 2017
Audentes Therapeutics (BOLD) started trading on the Nasdaq on 19 July 16
- Headquarters: San Francisco, CA
- Founded: 2012
- audentestx.com
Audentes sold 5 million shares at $15 apiece in its IPO. The $75 million raise will help Audentes fund clinical work it’s doing on rare diseases such as X-Linked myotubular myopathy, Crigler-Najjar Syndrome, and Pompe disease.
Description
Audentes Therapeutics, Inc. is an early-stage biotechnology company. The Company is focused on developing and commercializing gene therapy products for patients suffering from serious, life-threatening rare diseases caused by single gene defects. The Company has a portfolio of product candidates, including AT132 for the treatment of X-Linked Myotubular Myopathy (XLMTM); AT342 for the treatment of Crigler-Najjar Syndrome (Crigler-Najjar); AT982 for the treatment of Pompe disease, and AT307 for the treatment of the CASQ2 subtype of Catecholaminergic Polymorphic Ventricular Tachycardia (CASQ2-CPVT). The Company's subsidiary is Audentes Therapeutics UK Ltd. As of September 30, 2016, the Company had not generated any revenues.
Key stats and ratios
| Q2 (Jun '17) | 2016 | |
| Net profit margin | - | - |
| Operating margin | - | - |
| EBITD margin | - | - |
| Return on average assets | -58.78% | -45.98% |
| Return on average equity | -68.94% | -139.89% |
| Employees | 97 |
Secoo (SECO) started trading on the Nasdaq on 22 Sept 2017
Secoo prices its IPO of 8,500,000 American depositary shares at a price to the public of $13.00/ADS vs. expected range of $11.50-13.50, for a total offering size of approx. $110.50 mln
WASHINGTON, Sept 21 (Reuters Breakingviews) - A Chinese e-commerce startup is sitting in the lap of IPO luxury. Secoo has carved out a niche for itself in a cutthroat market, selling upscale brands such as Tod's and Versace. Though it's burning cash, the American depository shares on offer have a certain allure.
Secoo's customer base is smaller. Despite boasting some 15 million registered users, only 200,000 of them made at least one purchase during the first half of 2017. Yoox counted more than 3 million.
The Chinese firm nevertheless has its advantages. For one thing, Secoo customers aren't shy about spending. Average sales per order online was $516, more than $100 higher than at Yoox. Secoo also boasts some distinctly local edges. It caters specifically to posh tastes. That distinguishes it from the sprawling wares at larger rivals Alibaba and JD.com. Secoo also has yet to get tangled up in a counterfeit dispute.
Because Secoo has been losing money, albeit less of it than in previous years, traditional valuation methods are difficult. Based on its mooted price range, it would have a market capitalization of about $650 million. That's 1.7 times trailing revenue. Yoox trades at 1.3 times, as does $65 billion JD, which is also unprofitable using conventional American accounting guidelines.
In addition to its squeaky-clean image and extravagant clientele, Secoo is in a sweet spot. Consultancy Bain expects the market in which Secoo focuses to be the fastest-growing segment of China's luxury industry in coming years. That's one reason why deeper-pocketed Alibaba and JD are chasing high-end consumers, too.
Jack Ma's$450 billion colossus, however, is plagued by a reputation of having dodgy wares on its sites, which partly explains why only about a fifth of luxury brands are willing to set up shop on its Tmall, according to research outfit L2. JD, meanwhile, needs to reposition its mass-market image. Secoo, therefore, could make a tempting target for either company, and that is just one more reason why its shares may be a premium purchase.
Wednesday, September 20, 2017
Krystal Biotech (KRYS) started trading on the Nasdaq on 20 Sept 2017
- HQ: Pittsburgh, PA
- http://www.krystalbio.com/
- Founded: 2015
Krystal Biotech is a gene therapy company that is looking to bring products developed via its gene platform to the commercial market.
The company plans “to develop treatments for rare or orphan dermatological indications caused by the absence of or a mutation in a single gene, and plan to leverage our platform to expand our pipeline to include other dermatological indications in the future,” it said in its IPO filing.
The company’s leading product is known as KB103 and uses gene therapy to treat a rare genetic skin disease, dystrophic epidermolysis bullosa (DEB).
The disease currently has no approved treatment and those with it are often called “butterfly children” because the skin appears as fragile as butterfly wings.
KB103 is not yet in clinical trials.
The severest form of DEB is recessive DEB (RDEB), which “is characterized by severe skin blistering, extremely fragile skin, mutilating scarring of the hands and feet, joint contractures, strictures of the esophagus, and often, eventually the development of aggressive squamous cell carcinomas which may shorten the patient’s life,” the company said.
“Nearly 10% of RDEB patients die before the age of 10, almost 40% die by the age of 20, and over 70% die before the age of 30,” Krystal Biotech said.
Just One Gene Therapy Product Has the FDA’s OK
The market for the treatment would be 125,000 global patients, the company said, citing DEBRA International. There are about 3,200 to 3,500 patients in the U.S., European Union, Japan and Canada.
But here’s the big warning with the market opportunity for a gene therapy company.
“To date, only one gene therapy product has received marketing authorization from the FDA, and only two gene therapy products have received marketing authorization from the EMA,” Krystal Biotech said.
Monday, September 18, 2017
Nabriva Therapeutics (NBRV) : positive trial of pneumonia treatment
- www.nabriva.com
- HQ: Dublin, Ireland
- Founded in 2006
- IPO in 2015
- 59 Employees
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Nabriva Therapeutics plc, a clinical stage biopharmaceutical company, engages in the research and development of novel antibiotics to treat serious bacterial infections with a focus on the pleuromutilin class of antibiotics. Its lead product candidate is lefamulin, a novel semi-synthetic pleuromutilin antibiotic for systemic administration in humans. The company’s product, lefamulin is being studied in two registrational Phase 3 clinical trials in patients with moderate to severe community-acquired bacterial pneumonia. It is also developing lefamulin that has completed Phase 2 clinical trial for the treatment of acute bacterial skin and skin structure infections, as well as in preclinical studies for antibacterial activity against various gram-positive bacteria, gram-negative bacteria, and atypical bacteria, including multi-drug resistant strains. In addition, the company is developing BC-7013, a topical pleuromutilin product candidate, which has completed a Phase 1 clinical trial for the treatment of various gram-positive infections, including uncomplicated skin and skin structure infections. Nabriva Therapeutics plc was founded in 2006 and is based in Dublin, Ireland.
** charts before **
Friday, September 15, 2017
Neos Therapeutics (NEOS)
- Headquarters: Grand Prairie, TX
- Founded: 1994
- neostx.com
- IPO July 23, 2015; priced its IPO of 4.8M shares (up from 4M) of common stock at $15 per share.
The pharmaceutical firm develops products based on its proprietary modified-release drug delivery platform for the treatment of attention deficit hyperactivity disorder (ADHD). It currently markets only one product: a generic hydrocodone (narcotic cough suppressant) polistirex and chlorpheniramine (antihistamine) polistirex extended-release liquid suspension branded as Tussionex for the relief of cough and upper respiratory symptoms associated with allergy or cold in patients at least six years old.
Its three leading pipeline product candidates are: NT-0102, NT-0202 and NT-0201, all for the treatment of ADHD.
Neos Therapeutics receives U.S. FDA Approval of Adzenys ER (amphetamine) extended-release oral suspension for the treatment of ADHD in patients 6 years and older; to launch third medication in ADHD franchise in January 2018
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Description
Neos Therapeutics, Inc. is a pharmaceutical company. The Company is focused on developing, manufacturing and commercializing products utilizing its modified-release drug delivery technology platform. Its segment is engaged in the development, manufacturing and commercialization of pharmaceuticals. It has utilized its platform to develop its product for the treatment of attention deficit hyperactivity disorder (ADHD). Its product candidates are extended-release (XR), medications in patient-friendly, orally disintegrating tablets (ODT) or liquid suspension dosage forms. Its branded product and product candidates incorporate over two of the prescribed medications for the treatment of ADHD, methylphenidate and amphetamine. Its modified-release drug delivery platform has enabled it to create extended-release ODT and liquid suspension dosage forms of the medications. It focuses on developing Adzenys XR-ODT, Cotempla XR-ODT and NT-0201.
Key stats and ratios
| Q2 (Jun '17) | 2016 | |
| Net profit margin | -380.40% | -910.35% |
| Operating margin | -333.69% | -847.64% |
| EBITD margin | - | -799.06% |
| Return on average assets | -68.92% | -82.24% |
| Return on average equity | -394.99% | -216.94% |
| Employees | 134 |
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